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10.1016/j.cell.2017.09.021 Cell 117 SuiS
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Others may relate to blood sugar, appetite regulation, inflammation, blood pressure changes, lipid changes, or vascular effects being studied in the broader GLP-1 research landscape
Notably, compensatory crosstalk may limit monotherapy efficacymelanoma cells escaping ferroptosis via FSP1 upregulation may become more dependent on necroptosis suppression, and vice versaunderscoring the rationale for co-targeting multiple pathways to avoid adaptive resistance (114)
